Cardiac Sarcoidosis

Also known as: Sarcoidosis of the Heart

Cardiac Sarcoidosis is a rare condition characterised by the presence of granulomas, inflammatory nodules, in the heart muscle. Sarcoidosis is a multisystem inflammatory disease that can affect various organs, including the heart. When Sarcoidosis affects the heart, it can lead to serious complications, including heart rhythm disturbances, heart failure, and even sudden cardiac death.

What are the symptoms of Cardiac Sarcoidosis?

The symptoms of cardiac sarcoidosis can vary widely and may depend on the extent and severity of cardiac involvement. Common symptoms may include:

  • Palpitations or irregular heartbeat.

  • Chest pain or discomfort.

  • Shortness of breath, especially during exertion.

  • Fatigue or weakness.

  • Swelling in the legs, ankles, or feet (edema).

 

How is Cardiac Sarcoidosis diagnosed?

Diagnosing cardiac sarcoidosis can be challenging due to its nonspecific symptoms and variable presentation. Diagnostic tests may include:

Electrocardiogram (ECG/EKG):

This test records the heart's electrical activity and can detect abnormal heart rhythms or signs of myocardial ischemia.

Echocardiogram:

This ultrasound test provides images of the heart and can reveal abnormalities in heart size, shape, and function.

Cardiac MRI:

This imaging test can provide detailed images of the heart and detect areas of inflammation or scarring suggestive of cardiac sarcoidosis.

Positron Emission Tomography (PET) scan:

This imaging test can detect areas of inflammation or granuloma activity in the heart.

Endomyocardial Biopsy:

In some cases, a biopsy may be performed to obtain a small tissue sample from the heart for further evaluation under a microscope.

 

How is Cardiac Sarcoidosis treated?

Treatment for cardiac sarcoidosis aims to reduce inflammation, manage symptoms, and prevent complications. Treatment options may include:

Corticosteroids:

These anti-inflammatory medications are often used as first-line treatment to reduce inflammation and suppress the immune response.

Immunosuppressive Therapy:

In cases where corticosteroids alone are not effective, other immunosuppressive medications may be used to modulate the immune system and control inflammation.

Antiarrhythmic Medications:

Medications to manage abnormal heart rhythms may be prescribed to reduce the risk of arrhythmias and sudden cardiac death.

Heart Failure Medications:

Medications to manage symptoms of heart failure, such as ACE inhibitors, beta-blockers, and diuretics, may be prescribed to improve heart function and reduce fluid buildup.

Implantable Cardioverter-Defibrillator (ICD):

In patients at high risk of sudden cardiac death due to arrhythmias, an ICD may be implanted to monitor and treat life-threatening arrhythmias.

Early diagnosis and treatment are crucial for managing cardiac sarcoidosis and preventing complications. Individuals with symptoms suggestive of cardiac sarcoidosis should seek medical evaluation for proper diagnosis and treatment.

 

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Myocarditis